Synthesis of ringfluorinated thiophene derivatives based. Synthesis of new thiophene derivatives and their use as photostabilizers for rigid polyvinyl chloride january 2015 international journal of polymer science 20151. Cheminform is a weekly abstracting service, delivering concise information at a glance that was extracted from about 200 leading journals. All of these materials brought about a reduction in the level of photodegradation of polyvinyl chloride pvc films containing the synthesized thiophenes 0. Substituted thiophenes are among the most important aromatic heterocyclic derivatives. The objective of this present study is the synthesis of certain new. Pdf the use of thiophene derivatives that have a stable structure in agriculture, food and pharmaceutical industries has revealed the. Synthesis of ringfluorinated thiophene derivatives based on single cf bond activation of cf 3cyclopropanes.
The best known of the simple heterocyclic compounds are pyridine, pyrrole, furan, and thiophene. Reactions of the thiophene have been noted, along with useful spectroscopic and physical chemistry data as well as additional toxicity and ecotoxicity data for thiophene derivatives. Pdf synthesis of new thiophene derivatives and their use. Synthesis of new thiophene derivatives and their use as.
Nboc pyrrole was deprotonated upon treatment with litmp in. Pdf new thiophene derivatives as antimicrobial agents. Moreover, thiophene derivatives find large application in material science 515 and in coordination chemistry 16,17, and as intermediate in organic synthesis 18,19. The most common heterocycles are those having five or sixmembered rings and containing heteroatoms of nitrogen n, oxygen o, or sulfur s. Oriental journal of chemistry is abstracted and indexed in. Synthesis of arylsubstituted thieno3,2bthiophene derivatives and. Many thiophenes are prepared by processes involving a ring transformation, that is, conversion of other. The synthesis of brdntt features chemoselective metalation and crosscoupling reactions that enable us to keep the 2bromo group intact from the starting material.
This chapter covers aspects of the most recent developments in the synthesis and application of thiophene oligomers and polymers for use in a wide range of fields, from very efficient organic solar cells 2015nc10085 to fluorophores specifically binding amyloid fibrils formed inside neural cells in alzheimers and other neurodegenerative diseases. A series of ethyl2substituted benzylideneamino4,5,6,7tetrahydrobenzob thiophene 3carboxylate derivatives were synthesized by using gewald synthesis and their structures were confirmed by ftir, ms and 1hnmr. Sulfanylation and 5endotrig cyclization kohei fuchibe division of chemistry, faculty of pure and applied sciences, university of tsukuba, tsukuba, ibaraki 3058571, japan. To access a cheminform abstract, please click on html or pdf.
Pdf five new thiophenes, namely n3bromo2methylthiophen5yl methylene4methoxyaniline 4a. Thiophene and its monomethyl derivatives do not undergo coupling with diazonium salts in intermolecular reactions. Thiophene derivative an overview sciencedirect topics. Many molecules incorporating the thiophene nucleus. Biotic degradation of thiophene is minimal, and halothiophenes, in particular, are environmentally hazardous in aqueous systems. Pdf synthesis and characterization of the novel thiophene. A new series of thiophene analogues was synthesized and checked for their in vitro antibacterial, antifungal, antioxidant, anticorrosion and anticancer activities.
541 1461 766 1475 342 833 387 1036 352 225 433 782 1296 475 1097 13 206 871 98 667 118 1450 283 1374 501 1065 744 943 716 469 1260 645 1201 802 980 24 1290 646 482 939 898 1157